Creating Nanoparticles

Two approaches to nanoparticle creation

Quantachrome UK's sister site offers a range of Microfluidics products for creating nanoparticles.

Top down nanoparticle creation

Microfluidics LV1 low volume bench top machine brings high shear Microfluidizer processing capabilities to samples as small as 1 ml.

• Sample size: 1 ml to 6 ml per sample with operator settable volume control
• Shear rate: 12.25 million sec-1 at 2069 bar (30,000 psi)
• Uniform particle size reduction and cell disruption
• Nanoemulsions, nanosuspensions, nanoencapsulation

Utilizing Microfluidics’ fixed-geometry interaction chamber technology, the LV1 is capable of processing a wide variety of fluids such as oil-in-water emulsions, solids-in-liquid suspensions, and cells, including the most difficult yeasts and plant cells, in as few as 1-2 passes.

What’s more, the process is repeatable and is guaranteed to scale up to pilot and/or production volumes.

Bottom up nanoparticle creation

Microfluidics Reaction Technology (MRT) combines an impinging jet processor with application and process development to create nanoparticles bottom-up. Using continuous crystallization, chemical reactions and process intensification, MRT typically enables pharmaceutical, energy and chemical companies to achieve particle sizes impossible with any other method.

Applications of MRT:

• Continuous crystallization
• Efficient nanoencapsulation
• Chemical reactions
• Process intensification

For more information about nanoparticles, including top down and bottom particle creation, please visit our sister site Microfluidics UK.